Basal release of nitric oxide induces an oscillatory motor pattern in canine colon.
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چکیده
منابع مشابه
Dissociation of Basal and Stimulated Nitric Oxide Release
Background Endothelial dysfunction and abnormal vascular responsiveness to vasoconstrictors may play an important role in chronic heart failure (CHF). The purpose of our study was to (1) evaluate whether the vascular response to norepinephrine is abnormal in a rat model of heart failure; (2) investigate the role of a1and a2-adrenergic receptors; and (3) assess the contribution of the endotheliu...
متن کاملNebivolol induces nitric oxide release in the heart through inducible nitric oxide synthase activation.
Nebivolol is a beta1-adrenergic receptor antagonist that also reduces blood pressure by evoking endothelial NO production and vasodilation. We aimed at assessing whether nebivolol induces NO production also in the heart and delineating the molecular mechanisms involved. Using the fluorescent probe diaminofluorescein, we found that nebivolol induces a dose-dependent NO production in the heart, s...
متن کاملNebivolol Induces Nitric Oxide Release in the Heart Through Inducible Nitric Oxide
Nebivolol is a 1-adrenergic receptor antagonist that also reduces blood pressure by evoking endothelial NO production and vasodilation. We aimed at assessing whether nebivolol induces NO production also in the heart and delineating the molecular mechanisms involved. Using the fluorescent probe diaminofluorescein, we found that nebivolol induces a dose-dependent NO production in the heart, stati...
متن کاملAngiogenin induces nitric oxide release independently from its RNase activity.
Nitric oxide (NO), a biological mediator involved in vascular physiology, was sensed electrochemically using a microelectrode array. Angiogenin was shown to trigger nitric oxide synthase (NOS) activity in human umbilical vein endothelial cells and embryonic stem cell derived endothelial cells independently from its RNase activity.
متن کاملHemodynamic effects of basal and stimulated release of endogenous nitric oxide in isolated human lungs.
Background-We compared the hemodynamic responses to inhibition or stimulation of endothelial nitric oxide (NO) release of isolated explanted lungs from transplantation recipients with pulmonary hypertension and in normotensive unallocated donor lungs. Methods and Results-Lungs from 10 patients with severe pulmonary hypertension (SPH) and from 16 patients with severe chronic obstructive lung dis...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1997
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1997.sp021968